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YM022 is a highly potent
Simeprevir has been approved in Japan for the treatment of chronic hepatitis C infection
CAS Number: 198904-31-3
28-tetraazahexacyclo[16
TAS4464 hydrochloride thizole YM022 is a highly potentTAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0. 955 nM. Product information CAS Number: 1848959 11 4 Molecular Weight: 542. 97 Formula: C21H24ClFN6O6S Chemical Name: N {[(2R,3S,4R,5R) 5 {4 amino 5 [2 (2 ethoxy 6 fluorophenyl)ethynyl] 7H pyrrolo[2,3 d]pyrimidin 7 yl} 3,4 dihydroxyoxolan 2 yl]methyl}aminosulfonamide hydrochloride Smiles: Cl.