ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 size:10mg solid 32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4

32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4

NSC319726 was used at 1 µM in vitro and in cellular assays

CAS Number: 1962928-21-7

Smiles: CC1C=CC(=CC=1)C(=O)NCCCCCC(=O)NC1=CC=CC=C1N

ME0328 - PARP-3 Inhibitor. CAS# 1445251-22-8 size:10mg solid 32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4ME0328, CAS No. 1445251 22 8, is a potent, selective and cell permeable PARP 3 inhibitor with IC50 of 0. 89 M. It has good selectivity against PARP 1, PARP 2 and other ARDT enzymes. Enhances CRISPR Cas9 mediated HER2 mutation frequency, resulting in increased reduction in proliferation of HER2 positive breast cancer cells. Product information CAS Number: 1445251 22 8 Molecular Weight: 321. 37 Formula: C19H19N3O2 Chemical Name: (S) 3 (4 oxo 3,4