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Fotemustine cycline (hyclate) also known as SM04690

SKU: 16178409690

4.8
USD100.00 USD124.00

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Description

also known as SM04690

189232-42-6

such as antitumour

43(4):307-312

Fotemustine cycline (hyclate) also known as SM04690Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1 guanine and N3 cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood brain barrier. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).

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