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SKF-83566 hydrobromide Size:10mg solid InChi: InChI=1S/C37H45F4N5O13/c38-24-23-25(39)35(41)36(34(24)40)59-33(53)10-15-55-17-19-57-21-22-58-20-18-56-16-12-43-37(54)26(44-28(48)9-14-46-31(51)6-7-32(46)52)3-1-2-11-42-27(47)8-13-45-29(49)4-5-30(45)50/h4-7

SKU: 38036035303

4.4
USD140.00 USD162.00

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Description

InChi: InChI=1S/C37H45F4N5O13/c38-24-23-25(39)35(41)36(34(24)40)59-33(53)10-15-55-17-19-57-21-22-58-20-18-56-16-12-43-37(54)26(44-28(48)9-14-46-31(51)6-7-32(46)52)3-1-2-11-42-27(47)8-13-45-29(49)4-5-30(45)50/h4-7

Formula: C17H19N3O6

InChiKey: PEFASEPMJYRQBW-HKWQTAEVSA-N

Copenhagen DR

SKF-83566 hydrobromide Size:10mg solid InChi: InChI=1S/C37H45F4N5O13/c38-24-23-25(39)35(41)36(34(24)40)59-33(53)10-15-55-17-19-57-21-22-58-20-18-56-16-12-43-37(54)26(44-28(48)9-14-46-31(51)6-7-32(46)52)3-1-2-11-42-27(47)8-13-45-29(49)4-5-30(45)50/h4-7SKF 83566 hydrobromide is a potent, blood brain permeable and orally active D1 like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5 HT2 receptor (Ki=11 nM). SKF 83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5. 7 M. SKF 83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF 83566 can be used for the research of

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