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Panc-1 and BxPC3
Corrector-mediated rescue of misprocessed CFTR mutants can be reduced by the P-glycoprotein drug pump
HPTPβ and SHP2 with IC50s of 126 nM
Chemical Name: N1-(4-chlorophenyl)-6-methyl-N5-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1
SP-420 iaquine dihydrochloride Panc-1 and BxPC3SP 420 is a desferrithiocin analogue with iron clearing efficiency with ICE value of 26. 7; more potent than desferrithiocin. Product information CAS Number: 911714 45 9 Molecular Weight: 355. 41 Formula: C16H21NO6S Chemical Name: (4S) 2 {2 hydroxy 4 [2 (2 methoxyethoxy)ethoxy]phenyl} 4 methyl 4,5 dihydro 1,3 thiazole 4 carboxylic acid Smiles: COCCOCCOC1=CC(O)=C(C=C1)C1=N[C@](C)(CS1)C(O)=O InChiKey: YASYAEVZKXPYIZ MRXNPFEDSA N InChi: InChI=1S