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Losartan Carboxaldehyde 6681509 3-1(4)2(5)6/h8H

SKU: 98041466951

4.4
USD100.00 USD126.00

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Description

3-1(4)2(5)6/h8H

isolated from Nothapodytes foetida

5 µM) markedly reduces the COX-2 expression

4-triazin-3-one

Losartan Carboxaldehyde 6681509 3-1(4)2(5)6/h8HLosartan is an inhibitor of endothelial cyclooxygenase (COX) 2. COX 2 produces prostaglandins that inhibit apoptosis and stimulate angiogenesis and invasiveness, and thus selective COX 2 inhibitors can reduce prostaglandin synthesis and restore apoptosis. In vitro: Losartan is an intermediate aldehyde metabolite of losartan, the angiotensin II type 1 receptor antagonist. Losartan could not block angiotensin receptors, but inhibit the expression of

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