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Facial oedema is a characteristic of DRESS.[25] Ang et al reported in a series of 27 patients with DRESS syndrome, wherein 81.5% had an erythematous morbilliform rash involving the face, trunk, and limbs, 7.4% had generalised erythroderma, 7.4% had a pustular eruption, 7.4% had targetoid lesions, 29.6% had mucositis, and 33.3% had swelling of the face.[26] Systemic involvement Although the cutaneous eruption of DRESS is extensive and common, the major morbidity and mortality in DRESS result from systemic involvement

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