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STF-62247 shows cytotoxicity and tumor growth inhibitory activity against wild-type VHL and VHL-deficient renal cell carcinoma (RCC) in a HIF-independent manner with IC50 of 16 μM and 0
In multiple myeloma (MM) cells
InChi: InChI=1S/C17H13N5O2/c1-10-20-12-5-4-11(9-15(12)24-10)21-17(23)22-14-6-8-18-13-3-2-7-19-16(13)14/h2-9H
Formula: C31H44N2O5S
Vincristine domide-Propargyne-PEG3-COOH STF-62247 shows cytotoxicity and tumorVincristine (Leurocristine, NSC 67574, 22 Oxovincaleukoblastine) is a natural alkaloid isolated from the plant Vinca rosea Linn. with anti tumor activity. Vincristine inhibits microtubule formation in mitotic spindle and binds to microtubule with Ki of 85 nM. Product information CAS Number: 57 22 7 Molecular Weight: 824. 96 Formula: C46H56N4O10 Chemical Name: methyl 11 (acetyloxy) 12 ethyl 4 [17 ethyl 17 hydroxy 13 (methoxycarbonyl) 1,11
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