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Thalidomide-Piperazine 5-fluoride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology
thereby inducing marked peripheral vasodilation with negligible cardiodepression
N-desmethylclozapine and CPZ possibly act on neurotransmitter systems via modulation of TxA2 or TxB2 production
Phase II trial of carboxyamidotriazole in patients with relapsed epithelial ovarian cancer
Autotaxin-IN-3 19731 Thalidomide-Piperazine 5-fluoride is a synthesizedAutotaxin IN 3 is a Autotaxin(ATX) inhibitor with an IC50 of 2. 4 nM, compound 33, sourced from patent WO2018212534A1. Product information CAS Number: 2156655 68 2 Molecular Weight: 443. 46 Formula: C22H21N9O2 Chemical Name: 2 (5 {2 [(2,3 dihydro 1H inden 2 yl)amino]pyrimidin 5 yl} 1,3,4 oxadiazol 2 yl) 1 {3H,4H,5H,6H,7H [1,2,3]triazolo[4,5 c]pyridin 5 yl}ethan 1 one Smiles: O=C(CC1=NN=C(O1)C1=CN=C(NC2CC3C=CC=CC=3C2)N=C1)N1CC2NN=NC=2CC1 InChiKey:
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