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VU-29 lsulfathiazole CAS Number: 1014405-03-8

SKU: 1240972779

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CAS Number: 1014405-03-8

Epub 2015 Jun 23

Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins

Butein inhibits not only the EGF-stimulated auto-phosphotyrosine level of EGFR in HepG2 cells but also tyrosine-specific protein kinase activities of EGFR (IC50=16 μM) and p60c-src (IC50=65 μM) in vitro

VU-29 lsulfathiazole CAS Number: 1014405-03-8VU 29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor (EC50=9 nM and Ki=244 nM for rmGluR5). VU 29 is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1 rmGluR2=557 nM 1. 5 M; hmGluR4=154 nM). Product information CAS Number: 890764 36 0 Molecular Weight: 384. 39 Formula: C22H16N4O3 Chemical Name: N (1,3 diphenyl 1H pyrazol 5 yl) 4 nitrobenzamide Smiles: [O

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