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and irritation
Crew et al (2018) Identification and characterization of Von Hippel-Lindau-recruiting proteolysis targeting chimeras (PROTACs) of TANK-binding kinase 1
InChi: InChI=1S/C16H24N2O3
1446506-78-0
JSH-23 - CAS# 749886-87-1 Catalog No.:M9452-10 and irritationJSH 23 is a nuclear factor kappa B (NF B) nuclear translocation inhibitor. JSH 23 inhibits LPS and cytokine induced nuclear translocation of the p65 subunit of NF kB as analyzed by EMSA and western blot. JSH 23 treatment significantly reversed the nerve conduction and nerve blood flow deficits seen in diabetic animals. Reduction in mechanical pain threshold was also partially corrected by the treatment. Protein expression studies showed that nuclear
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