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Complete inhibition of tumor growth was achieved in the PC3 xenograft model and shown to be schedule dependent
SDMA increases during disease progression
Like protease inhibitors
5-dimethyloxan-2-yl]-2
Hycanthone dartinib Complete inhibition of tumor growthHycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease 1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY B2098) and has anti schistosomal agent. Product information CAS Number: 3105 97 3 Molecular Weight: 356. 48 Formula: C20H24N2O2S Chemical Name: 1
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