JH-XI-10-02 Catalog No.:M14601-2 4-diethoxyphenyl)-1

4-diethoxyphenyl)-1

GNE-140 inhibits proliferation in 37 of 347 cancer cell lines tested at a potency cut off of 5 μM

and LNCaP cells with IC50 of 72 nM

Tolycaine also causes convulsions in vivo

JH-XI-10-02 Catalog No.:M14601-2 4-diethoxyphenyl)-1JH XI 10 02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH XI 10 02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH XI 10 02 shows no effect on CDK19. Product information CAS Number: 2209085 22 1 Molecular Weight: 920. 14 Formula: C53H69N5O9 Chemical Name: N [(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS) 3a,3b,5a,9b tetrahydrogenio 1 (isoquinolin 7 yl) 9a,11a dimethyl hexadecahydro 1H cyclopenta[a]phenanthren