mTOR-IN-1 - CAS# 1207358-59-5 Catalog No.:M9817-2 Note that in order to

Note that in order to examine a direct GPR119 effect

InChiKey: YJDYDFNKCBANTM-QCWCSKBGSA-N

InChiKey: VNONINPVFQTJOC-ZGXDEBHDSA-N

9)6-4-2-1-3-5-6/h3-10

mTOR-IN-1 - CAS# 1207358-59-5 Catalog No.:M9817-2 Note that in order tomTOR IN 1 is a remarkably selective mTOR inhibitor with a Ki of 1. 5 nM. mTOR IN 1 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK) pharmacodynamic (PD) experiments. In Vitro: mTOR IN 1 (Compound 12i) inhibits mTOR with a Ki of 1. 5 nM, 500 fold selectivity over closely related PI3 kinases. mTOR IN 1 inhibits NCI PC3 and MCF7neo Her2 cells proliferation with IC50s of 150 nM and 57 nM, respectively[2]. In Vivo: mTOR IN 1