DDMS - CAS# 206052-03-1 )-87 InChiKey: XQQYORJJFZQWNA-UHFFFAOYSA-N

InChiKey: XQQYORJJFZQWNA-UHFFFAOYSA-N

PubMed PMID: 22396724

A small molecule differentiation inducer increases insulin production by pancreatic β cells

Smiles: O=C(CSC1N=C(CCC2C=CC=CC=2)N=C2SC3CCCCC=3C2=1)NC1=CC=CC=C1N1CCOCC1

DDMS - CAS# 206052-03-1 )-87 InChiKey: XQQYORJJFZQWNA-UHFFFAOYSA-NDDMS is a CYP4A2 enzyme inhibitor. Biosynthesis of 20 HETE from arachidonic acid by the cytochrome P450 4A (CYP450 4A) isoforms is a key component of vascular homeostasis, especially in renal circulation. In vitro: To determine whether inhibition of 20 HETE contributes to the vasodilatory effects of NO, the effects of DDMS on the response to SNP were examined in rat renal arterioles preconstricted with phenylephrine). Results showed that after DDMS