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Paltusotine (CRN00808) is an orally active
InChi: InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H
Smiles: CC1=C2[C@@H](O)[C@](C)(CO)C=C2C(=O)[C@](C)(O)C21CC2
and cutaneous and vaginal candidiasis
ONO 4817 707enbufen Paltusotine (CRN00808) is an orallyONO 4817 is a potent inhibitor of MMP 2, MMP 3, MMP 7, MMP 9, MMP 12 and MMP 13 with IC50 value of 0. 73 nM, 42 nM, 2500 nM, 1. 1 nM, 2. 1 nM, 0. 45 nM and 1. 1 nM, respectively . Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that belong to the metzincin superfamily and play an important role in tissue remodeling associated with various physiological or pathological processes such as morphogenesis, angiogenesis, tissue repair,
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