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and wound healing properties
CAS Number: 1207989-09-0
1-trichloro-2-methylpropan-2-ol) hydrate
Epub 2013 Sep 27
O-1602 Catalog No.:M22717-C and wound healing propertiesO 1602 is an agonist of GPR55 (EC50 = 13 nM in a GTPS binding assay) and a derivative of the GPR55 agonist abnormal cannabidiol. It is selective for GPR55 over cannabinoid (CB) receptor 1 (CB1) and CB2 (EC50s = >30 M for both in GTPS binding assays). O 1602 (50 M) reduces growth of Mz ChA 1, HuCCT 1, CC LP 1, and SG231 cholangiocarcinoma cells and reduces tumor growth in a Mz ChA 1 mouse xenograft model when administered at a dose of 10 mg kg per day.