AG 556 Catalog No.:M23088-C It is more than 40-fold

It is more than 40-fold selective for CDK7 than CDK1

4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H

Triptonide can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin

Verucopeptin attenuates the phosphorylation of most of the tested mTORC1 downstream substrates

AG 556 Catalog No.:M23088-C It is more than 40-foldAG 556 is a selective inhibitor of EGFR with IC50 value of 1. 1 M. The epidermal growth factor receptor (EGFR) is the cell surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. AG 556 is a selective EGFR inhibitor. In HEK 293 cells expressing KIR2. 3 or Kir2. 1, AG556 (10 M) reversibly reduced KIR2. 3 or Kir2. 1 currents. Also, AG556 inhibited tyrosine phosphorylation of KIR2. 3 or