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Amifostine thiol dihydrochloride - CAS# 14653-77-1 Size:2mg solid 5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid

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Description

5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid

and dose-dependently suppresses VEGF-induced survival and migration of endothelial cells in the same dose range without cytotoxic or antiproliferative effect on cells that do not express VEGF receptors

suppresses the effects of Aβ42-lowering γ-secretase modulators

A selective IKK-2 inhibitor blocks NF- k B-dependent gene expression in interleukin-1ß-stimulated synovial fibroblasts

Amifostine thiol dihydrochloride - CAS# 14653-77-1 Size:2mg solid 5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acidAmifostine thiol (WR 1065) dihydrochloride can protect normal tissues from the toxic effects of certain cancer drugs and activate p53 through a JNK dependent signaling pathway. Product information CAS Number: 14653 77 1 Molecular Weight: 207. 16 Formula: C5H16Cl2N2S Synonym: WR 1065 dihydrochloride Chemical Name: 2 [(3 aminopropyl)amino]ethane 1 thiol dihydrochloride Smiles: Cl. Cl. NCCCNCCS InChiKey: XDRLRDHLCIFZIW UHFFFAOYSA N InChi: InChI=1S

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