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ClH/c1-24-18-6-3-13(9-19(18)25-2)7-8-20-11-14(21)12-26-15-4-5-16(22)17(23)10-15
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia
InChi: InChI=1S/C13H25BrO5/c1-13(2
(E/Z)-Sivopixant (Compound I-127) is a potent P2X3 receptor antagonist with an IC50 of 4 nM
A 412997 dihydrochloride Size:Contact [email protected] for quotation ClH/c1-24-18-6-3-13(9-19(18)25-2)7-8-20-11-14(21)12-26-15-4-5-16(22)17(23)10-15A 412997 dihydrochloride is a selective agonist of dopamine D4 receptor with Ki values of 7. 9 and 12. 1 nM for human and rat D4 receptors, respectively . Dopamine D4 receptor is a G protein coupled receptor and is activated by dopamine. It plays an important role in cognition, Parkinsons disease, addictive behaviors and so on. A 412997 dihydrochloride is a selective dopamine D4 receptor agonist. In calcium flux functional assays, A 412997 activated