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11(11):2499-507
2013 Jun 19
S)-AHPC-phenol-alkylC6-amine (dihydrochloride) is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC
Woodhead SJ
Thalidomide-Propargyne-PEG2-COOH lafenamide hemifumarate 11(11):2499-507Thalidomide Propargyne PEG2 COOH is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Product information Molecular Weight: 428. 39 Formula: C21H20N2O8 Chemical Name: 3 [2 ({3 [2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 5 yl]prop 2 yn 1 yl}oxy)ethoxy]propanoic acid Smiles: OC(=O)CCOCCOCC#CC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O
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