Tivozanib (hydrate) Size:Contact [email protected] for quotation Chemical Name: (2S)-2-amino-5-[(E)-N''-methylcarbamimidamido]pentanoic acid

Chemical Name: (2S)-2-amino-5-[(E)-N''-methylcarbamimidamido]pentanoic acid

MK0752 is a synthetic small molecule with potential antineoplastic activity

7aS)-4-[(acetyloxy)methyl]-7-hydroxy-1

13-25)19(27)28-3

Tivozanib (hydrate) Size:Contact [email protected] for quotation Chemical Name: (2S)-2-amino-5-[(E)-N''-methylcarbamimidamido]pentanoic acidTivozanib, also known as AV 951 and KRN 951, is an orally active, ATP competitive, small molecule, quinoline urea derivative. Tivozanib is a pan VEGFR tyrosine kinase inhibitor. In vitro: Tivozanib markedly inhibited the ligand induced phosphorylation of VEGFR1\2 and 3 with the IC50 value of 30 nM\6. 5 nM and 15 nM, respectively. Tivozanib also exihibited inhibitory effects on PDGFR and c Ki with the IC50 value of 1. 72 and 1. 63 nmol L, respectively.