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91(20):13080-13087
CAS Number: 2308497-58-5
Advances in Long- Acting Agents for the Treatment of HIV Infection
Naquotinib (ASP8273) is an orally available
VU0364572 (trifluoroacetate salt) 247egeline 91(20):13080-13087IC50: 477 172 nM VU0364572 is a M1 agonist. Alzheimer's disease (AD) is the leading cause of dementia worldwide, and no disease modifying therapy is availables. Selective M1 muscarinic acetylcholine receptor activation is an attractive mechanism for AD therapy since M1 mediates key effects on cognition, memory, and behavior and has potential for disease modifying effects on A formation and tau phosphorylation. In vitro: Previous study found that
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