c-Kit-IN-3 Size:Contact [email protected] for quotation Chemical Name: 2-[2-chloro-N-(3-chloro-4-methoxyphenyl)acetamido]-N-(2-phenylethyl)-2-(thiophen-2-yl)acetamide

Chemical Name: 2-[2-chloro-N-(3-chloro-4-methoxyphenyl)acetamido]-N-(2-phenylethyl)-2-(thiophen-2-yl)acetamide

and partially corrects macroorchidism

35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10

Smiles: CCCCC=CCCCCCC1=CC(=O)C2=CC=CC=C2N1C

c-Kit-IN-3 Size:Contact [email protected] for quotation Chemical Name: 2-[2-chloro-N-(3-chloro-4-methoxyphenyl)acetamido]-N-(2-phenylethyl)-2-(thiophen-2-yl)acetamidec Kit IN 3 (Compound 18) is a potent and selective c KIT kinase inhibitor with an IC50 of 4 nM. c Kit IN 3 displays great potencies against c KIT kinase and a broad spectrum of drug resistant mutants in the biochemical assay. c Kit IN 3 has improved bioavailability. c Kit IN 3 (Compound 18; 0. 1 10 M; 6 days; primary GIST patient cells) exhibits dose dependent antiproliferative effects. c Kit IN 3 (Compound 18; 0. 01 1 M; 24 hours; GIST T1, GIST T1