Kinetin riboside enofovir maleate SB590885 decreases anchorage-independent growth of

SB590885 decreases anchorage-independent growth of melanoma cell lines in a BRAF mutant-selective manner

In vivo toxicity assessment experiments show that ONC212 is well tolerated up to 250 mg/kg

PubMed PMID: 29079285

CAS Number: 1082744-20-4

Kinetin riboside enofovir maleate SB590885 decreases anchorage-independent growth ofKinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT 15 cells with an IC50 of 2. 5 M. Product information CAS Number: 4338 47 0 Molecular Weight: 347. 33 Formula: C15H17N5O5 Synonym: N6 Furfuryladenosine Chemical Name: (2R, 3R, 4S, 5R) 2 (6 {[(furan 2 yl)methyl]amino} 9H purin 9 yl) 5 (hydroxymethyl)oxolane 3, 4 diol Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2C(NCC3=CC=CO3)=NC=NC1=2