Aeroplysinin 1 NX-774 The novel Aurora A kinase

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

CAS Number: 312749-73-8

and increases the apoptosis rate at the high concentration (≥10 μM)

1996 Feb 2

Aeroplysinin 1 NX-774 The novel Aurora A kinaseAeroplysinin 1 ((+) Aeroplysinin 1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram positive bacteria and exerts antiviral activity against HIV 1 (IC50=14. 6 M). Aeroplysinin 1 has anti inflammatory, anti angiogenic and anti tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells. Product information CAS Number: 28656 91 9 Molecular Weight: 338. 98 Formula: C9H9Br2NO3 Chemical Name: 2