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Development of dimeric modulators for anti-apoptotic Bcl-2 proteins
and almost no inhibitory effect on emotional reactions
For WI-38 and BPH-1 cells
InChi: InChI=1S/C22H21FN4O3S/c1-4-27-13-24-21-18(12-25-26-22(21)27)14-6-9-19(23)17(10-14)16-8-7-15(11-20(16)30-3)31(28
MCL-1/BCL-2-IN-2 173v3 modulator 1 Development of dimeric modulators forMCL 1 BCL 2 IN 2 (Compound 6) is a potent and selective Mcl 1 and Bcl 2 dual inhibitor. Product information CAS Number: 2163793 44 8 Molecular Weight: 427. 31 Formula: C20H15BrN2O2S Chemical Name: 3 (2 aminoethyl) 8 [(4 bromophenyl)sulfanyl] 3 azatricyclo[7. 3. 1. 0,]trideca 1(13),5,7,9,11 pentaene 2,4 dione Smiles: NCCN1C(=O)C2C=CC=C3C=2C(=CC=C3SC2C=CC(Br)=CC=2)C1=O InChiKey: LPOALFWTLPKKNW UHFFFAOYSA N InChi: InChI=1S C20H15BrN2O2S c21 12 4 6 13(7 5
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