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Methyl (E)-cinnamate (EMC)
Smiles: CC1=CC(=CC(=C1F)C(=O)NNS(=O)(=O)C1=CC(O)=CC=C1)C1C=CC=CC=1
24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2
which inhibits RSK1
Gap19 amine A-D3 Methyl (E)-cinnamate (EMC)Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40 pannexin 1 hemichannels. Gap19 has protective effects against myocardial. Product information CAS Number: 1507930 57 5 Molecular Weight: 1161. 44
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