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Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
It is a non-ATP competitive inhibitor of MEK1/2 (IC50 ~ 12 nM)
1996 Jan 5
2012 Jan 15
MAL-HA-OSu - CAS# 55750-63-5 022 Small molecule-mediated disruption of Wnt-dependentEMCS crosslinker, also known as Mal heptanoic NHS ester, CAS No. 55750 63 5, is a non cleavable, water insoluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibodies. EMCS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moieties, respectively. The EMCS Crosslinker may be useful in the development of antibody drug
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