Selumetinib sulfate 1123 K562 cells) treatment inhibits MAPK/ERK/JNK

K562 cells) treatment inhibits MAPK/ERK/JNK downstream signaling and diminishes Jak2/Stat3/Akt expression

11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-5-(propan-2-yl)-2

Smiles: NC1=CC=CC=C1NC(=O)C1C=CC(CNC2N=CC=C(N=2)C2=CC=CN=C2)=CC=1

Tacalcitol monohydrate is is a D3 derivative

Selumetinib sulfate 1123 K562 cells) treatment inhibits MAPK/ERK/JNKSelumetinib (AZD6244) is selective, non ATP competitive oral MEK1 2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1 2 phosphorylation. Product information CAS Number: 943332 08 9 Molecular Weight: 555. 76 Formula: C17H17BrClFN4O7S Chemical Name: 5 [(4 bromo 2 chlorophenyl)amino] 4 fluoro N (2 hydroxyethoxy) 1 methyl 1H 1,3 benzodiazole 6 carboxamide; sulfuric acid Smiles: