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may be a useful agent for the study of AhR-mediated signal transduction and the prevention of TCDD-associated pathology
Solubility: DMSO : 100 mg/mL (376
InChi: InChI=1S/C30H36N4O2
8(6):1957-63
JNK Inhibitor VIII ramide A (NPI-0052) may be a useful agentJNK Inhibitor VIII (TCS JNK 6o) is an inhibitor of c Jun N terminal kinases with IC50 of 45 nM and 160 nM for JNK 1 and JNK 2, respectively. JNK Inhibitor VIII (TCS JNK 6o) inihibits JNK 1, JNK 2, and JNK 3 with Ki of 2 nM, 4 nM and 52 nM, respectively. Product information CAS Number: 894804 07 0 Molecular Weight: 356. 38 Formula: C18H20N4O4 Synonym: TCS JNK 6o Chemical Name: N (4 Amino 5 cyano 6 ethoxy 2 pyridinyl) 2,5 dimethoxybenzeneacetamide