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ClH/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22
At 24 hours postdose
It inhibits the growth of a variety of human cancer cell lines with IC50 ranging from 60 to 200 nM
beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells
Thienyldecyl Isothiocyanate let-7a antagonist 1 ClH/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22Thienyldecyl isothiocyanate is a cytochrome P450 inhibitor . The human cytochrome P450 (CYP), a cellular chromophore, has been implicated in metabolism of drugs, arachidonic acid, foreign chemicals, and eicosanoids; steroid synthesis and metabolism; vitamin D3 synthesis and metabolism; cholesterol metabolism and bile acid biosynthesis; retinoic acid hydroxylation. Until now, there are more than 270 different CYP gene families have been identified,
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