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displaying greater than 7700-fold selectivity versus BRD4 (1
Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770 μM
MYC is a major oncogenic transcriptional driver of most human cancers that has remained intractable to direct targeting because much of MYC is intrinsically disordered
Thailanstatin C inhibits human cancer cell lines with IC50s of 2
Hecogenin acetate talopram hydrobromide displaying greater than 7700-fold selectivityHecogenin acetate is a steroidal sapogenin acetylated with anti inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors. Product information CAS Number: 915 35 5 Molecular Weight: 472. 66 Formula: C29H44O5 Chemical Name: (1'R,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'S,16'S,18'S) 5,7',9',13' tetramethyl 10' oxo 5' oxaspiro[oxane 2,6' pentacyclo[10. 8. 0. 0,. 0,.