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4)15-17-31(24
) inhibits XBP1 splicing in a model of ER stress in vivo
InChiKey: BPMFZUMJYQTVII-UHFFFAOYSA-N
InChi: InChI=1S/C17H24N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4
JMS-053 Size:Contact [email protected] for quotation 4)15-17-31(24JMS 053 is a potent, selective and reversible PTP4A inhibitor, with IC50s of 29. 1 nM, 48. 0 nM, 34. 7 nM, 92. 6 nM, and 207. 6 nM for PTP4A1, PTP4A2, PTP4A3, CDC25B, and DUSP3, respectively. JMS 053 can inhibit cancer cell migration and spheroid growth in vitro, attenuate in vivo ovarian tumor growth. Product information CAS Number: 1954650 11 3 Molecular Weight: 256. 28 Formula: C13H8N2O2S Smiles: N=C1C2SC(=CC=2C(=O)NC1=O)C1C=CC=CC=1 InChiKey:
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