![D77 ram sodium salt COC1C=C(C=C(OC)C=1OC)C(=O)O[C@@H]1C[C@@H]2CN3CCC4C5=CC=C(C=C5NC=4[C@H]3C[C@@H]2[C@@H]([C@H]1OC)C(=O)OC)OC](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M21578_1635218899.gif?v=1635218900)
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COC1C=C(C=C(OC)C=1OC)C(=O)O[C@@H]1C[C@@H]2CN3CCC4C5=CC=C(C=C5NC=4[C@H]3C[C@@H]2[C@@H]([C@H]1OC)C(=O)OC)OC
α-NETA induces pyroptosis of epithelial ovarian cancer cells through the GSDMD/caspase-4 pathway
Formula: C19H19Cl2FN2O3S
Costunolide has been reported for the wide spectrum of biological effects
D77 ram sodium salt COC1C=C(C=C(OC)C=1OC)C(=O)O[C@@H]1C[C@@H]2CN3CCC4C5=CC=C(C=C5NC=4[C@H]3C[C@@H]2[C@@H]([C@H]1OC)C(=O)OC)OCD77 is anti HIV 1 inhibitor targeting the interaction between integrase and cellular LEDGF p75. D77 inhibits HIV 1(IIIB) replication by EC50 value of 23. 8 g ml in MT 4 cell (5. 03 g ml for C8166 cells). IC50 value: 23. 8 g ml (EC50, in MT 4 cell ), 5. 03 g ml (EC50, in C8166 cell)Target: HIV 1in vitro: D77 exhibits a highly specific binding affinity to HIV 1 integrase catalytic core domain. D77 induces a dramatic concentration dependent decrease of
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