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Chemical Name: 5-beta-Cholest-7-en-6-one
as well as in cells harbouring the T790M mutation
Smiles: CC(O)(CS(=O)(=O)C1C=CC(F)=CC=1)C(=O)NC1=CC(=C(C=C1)C#N)C(F)(F)F
33)24-11-5-7-20-6-1-2-8-21(20)24
K-Ras ligand-Linker Conjugate 1 pyrrole A Chemical Name: 5-beta-Cholest-7-en-6-oneK Ras ligand Linker Conjugate 1 incorporates a ligand for K Ras, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K Ras ligand Linker Conjugate 1 can be used in the synthesis of PROTAC K Ras Degrader 1 (HY 129523), which is potent PROTAC K Ras degrader that exhibits 70% degradation efficacy in SW1573 cells. Product information Molecular Weight: 826. 94 Formula: C43H54N8O9 Chemical Name: benzyl (2S) 2 (cyanomethyl) 4 (2
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