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SNIPER(ABL)-013 28170 Smiles: CN1C2=C(C=NN(CC3=CC(N)=CC=C3)C2=O)C2SC(=CC1=2)S(C)=O

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Description

Smiles: CN1C2=C(C=NN(CC3=CC(N)=CC=C3)C2=O)C2SC(=CC1=2)S(C)=O

intermediate duration of action

CAS Number: 6035-45-6

ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20

SNIPER(ABL)-013 28170 Smiles: CN1C2=C(C=NN(CC3=CC(N)=CC=C3)C2=O)C2SC(=CC1=2)S(C)=OSNIPER(ABL) 013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR ABL protein with a DC50 of 20 M. Product information Molecular Weight: 839. 90 Formula: C42H52F3N7O8 Chemical Name: (2S) 2 [(2S, 3R) 3 amino 2 hydroxy 4 phenylbutanamido] 4 methyl N (2 {2 [2 (2 {[3 (6 {[4 (trifluoromethoxy)phenyl]amino}pyrimidin 4 yl)phenyl]formamido}ethoxy)ethoxy]ethoxy}ethyl)pentanamide Smiles:

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