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13(9):2771-2782
Sulfapyridine is a sulfonamide antibacterial
InChi: InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10
37-trimethoxy-12
Mutant IDH1-IN-2 ecyl sulfate D25 13(9):2771-2782Mutant IDH1 IN 2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS MS biochemical assay, IC50 of 16. 6 nM in Fluorescence biochemical assay. Target: Mutant IDH1Mutant IDH1 IN 2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell proliferation disorders, such as cancer. More bioactivity information in Patent WO
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