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2014:149628
Chemical Name: 2-({[(2-oxothiolan-3-yl)carbamoyl]methyl}sulfanyl)acetic acid
and monkey and low predicted clearance in human
Research Article Volume 2017
ICA-105665 Catalog No.:M15782-C 2014:149628ICA 105665 (PF 04895162) is a potent and orally active neuronal Kv7. 2 7. 3 and Kv7. 3 7. 5 potassium channels opener. ICA 105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 M). ICA 105665 can penetrate the blood brain barrier and has antiseizure effects. Product information Molecular Weight: 355. 34 Formula: C19H15F2N3O2 Chemical Name: N (2 cyclopropyl 7 fluoro 4 oxo 3,4 dihydroquinazolin 3 yl) 2
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