GNE-6468 Catalog No.:M21940-C has both antidepressant-like effects and

has both antidepressant-like effects and synergizes with desipramine in an animal model of depression

The drug is safe owing to low systemic absorption and has only minimal side-effect of local irritation at the site of application

Smiles: C[C@]12CC[C@H](O)C[C@@H]1C(=O)C[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2C

06 nM) and CM235 (IC50 = 0

GNE-6468 Catalog No.:M21940-C has both antidepressant-like effects andGNE 6468 is a highly potent and selective ROR (RORc) inverse agonist with an EC50 value of 13 nM for HEK 293 cell. GNE 6468 exhibits an EC50 of 30 nM for IL 17 PBMC. Product information CAS Number: 1677668 27 7 Molecular Weight: 433. 84 Formula: C23H16ClN3O4 Chemical Name: 4 [6 (2 chloro 6 cyclopropylbenzoyl)imidazo[1,5 a]pyrimidin 8 yl] 2 hydroxybenzoic acid Smiles: OC(=O)C1=CC=C(C=C1O)C1N=C(C(=O)C2C(Cl)=CC=CC=2C2CC2)N2C=CC=NC2=1 InChiKey: