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Exherin trifluoroacetate - CAS# 1135237-88-5 hemisulfate 16(7):e314

SKU: 25984069998

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Description

16(7):e314

Single agent therapy results in significant tumor growth inhibition in animals treated with entrectinib compared to control animals

InChi: InChI=1S/C26H31BrN8O/c1-18-15-20(31-36-18)17-33-9-13-35(14-10-33)24-22(27)16-28-26-23(24)29-25(30-26)19-3-5-21(6-4-19)34-11-7-32(2)8-12-34/h3-6

DHE-derived fluorescence at 570 nm is a convenient method for detection of intracellular and extracellular superoxide produced by phagocytic and vascular NADPH oxidase

Exherin trifluoroacetate - CAS# 1135237-88-5 hemisulfate 16(7):e314Exherin TFA salt, also known as ADH 1 TFA, is the TFA salt form of exherin, which is a small, cyclic pentapeptide vascular targeting agent with potential antineoplastic and antiangiogenic activities. ADH 1 selectively and competitively binds to and blocks N cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N cadherin, a cell surface

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