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]dec-7-en-10-yl]oxy}oxan-2-yl]methyl (2E)-3-phenylprop-2-enoate
MCL-1/BCL-2-IN-4 (Compound 7) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor
extracted from patent WO 2013059666A1
PMCID: PMC6557692
EUK 134 bridin ]dec-7-en-10-yl]oxy}oxan-2-yl]methyl (2E)-3-phenylprop-2-enoateEUK 134, a synthetic superoxide dismutase (SOD) catalase mimetic, has exhibited potent antioxidant activities and inhibited the formation of amyloid and related amyloid fibril. In vitro: EUK 134, a salen manganese complex, showed potent catalase and cytoprotective activities and SOD activity. After middle cerebral artery occlusion, EUK 134 administration at 3 hr significantly reduced brain infarct size, with the highest dose apparently preventing