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550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection
16(3):312-7
the peculiar interaction of LT175 with PPARγ could affect the recruitment of the coregulators cyclic-AMP response element-binding protein-binding protein and nuclear corepressor 1
In a dose kinetics experiment
MBM-17S Catalog No.:M23679-C 550: a potent and selectiveMBM 17S is a potent NIMA related kinase 2 (Nek2) inhibitor, with an IC50 of 3 nM. MBM 17S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM 17S shows antitumor activities, and no obvious toxicity to mice. Product information CAS Number: 2083621 91 2 Molecular Weight: 716. 74 Formula: C36H40N6O10 Chemical Name: 2 (benzyloxy) 4 (7 {1 [2 (dimethylamino)ethyl] 1H pyrazol 4 yl}imidazo[1,2 a]pyridin 3
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