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a potent mGluR5 silent allosteric modulator (SAM)
Chemical Name: (2R)-2-[(2-amino-5-{[(1S)-1-phenylethyl]sulfanyl}-[1
3R)-2-({[(1S)-2-carbamoyl-1-[3-(piperazin-1-yl)-1
CAS Number: 54149-17-6
Rac-Nedisertib purogallin a potent mGluR5 silent allostericRac Nedisertib (Rac M3814) is a racemate of Nedisertib, a potent DNA PK inhibitor, with an IC50 of <3 nM. DNA PK <3 nM (IC50) Rac Nedisertib (Compound 137) potently inhibits DNA PK, with an IC50 of <3 nM for DNA PK, 0. 5 5 M for cellular pDNA PK and 15 25 M for KV11. 1 (hERG, human ether a go go related gene) ).. . Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1. Product information CAS Number: 1637542 34 7 Molecular Weight: 481. 91 Formula:
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