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InChiKey: PIPZGJSEDRMUAW-ZKKXXTDSSA-N
Prog Drug Res
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Santamarina E
OG-L002 HCl 2623 InChiKey: PIPZGJSEDRMUAW-ZKKXXTDSSA-NOG L002 is a specific and potent inhibitor of lysine (K) specific demethylase 1A (LSD1) with IC50 value of 20 nM . LSD1 is a flavin dependent monoamine oxidase, which can demethylate lysines. LSD1 plays critical roles in oocyte growth, embryogenesis and tissue specific differentiation . OG L002 potently inhibited HSV IE gene expression in both HFF and HeLa cells with IC50 of ~3 M and ~10 M, respectively. OG L002 treatment can potently reduce
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