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C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16
(2013) Elife
4 nM) and FLT3 (IC50 of 30
Smiles: C[C@]1(NC2=C(C1=O)[C@@]13C[C@@H]1CN(C3=CC2=O)C(=O)C1=CC2=CC(OC)=C(OC)C(OC)=C2N1)C(=O)OC
O-1918 Size:Contact [email protected] for quotation C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16Abnormal cannabidiol is a synthetic regioisomer of cannabidiol that fails to elicit either central cannabinoid (CB1) or peripheral cannabinoid (CB2) responsiveness and is without psychotropic activity. It induces endothelium dependent vasodilation via a CB1 CB2 nitric oxide independent mechanism. O 1918 is a cannabidiol analog that acts as a selective antagonist of abnormal cannabidiol at the non CB1 CB2 endothelial receptor. It does not bind to CB1