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Vassilev LT
15(11):21419-32
InChi: InChI=1S/C45H72O16/c1-21(47)56-26-19-55-38(34(31(26)51)57-22(2)48)60-28-11-13-45-20-44(45)15-14-41(7)35(43(9)12-10-29(61-43)40(5
RVX-208: a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo
Docetaxel gobuvir Vassilev LTDocetaxel, also known as RP 56976, is a semi synthetic, second generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell cycle arrest at the G2 M phase and cell death. This agent also inhibits pro angiogenic factors such as vascular endothelial growth factor
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