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11(3):1039-1044
) as a single agent (top panel) or in combination with radiation (bottom panel) results in an increase in fluorescence intensity in the Calu-6 tumors
InChi: InChI=1S/C26H24ClN3O3
because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen
Bendamustine Hydrochloride ntan Hydrochloride 11(3):1039-1044Bendamustine is a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and
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