Vandetanib Hydrochloride Catalog No.:M9560-10 0-90 min) induces lysis of

0-90 min) induces lysis of Tol+and Tol- strains

12(3):441-452

InChiKey: GUQNHCGYHLSITB-UHFFFAOYSA-N

57% of viruses with genotypes containing Y181C as a single NNRTI mutation (43% for efavirenz)

Vandetanib Hydrochloride Catalog No.:M9560-10 0-90 min) induces lysis ofVandetanib is an orally bioavailable 4 anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell