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Cetirizine dihydrochloride thine HCl H2O InChiKey: GROMEQPXDKRRIE-UHFFFAOYSA-N

SKU: 30733723466

4.8
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Description

InChiKey: GROMEQPXDKRRIE-UHFFFAOYSA-N

induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway

In nasopharyngeal epithelial cells

Chemical Name: (3S

Cetirizine dihydrochloride thine HCl H2O InChiKey: GROMEQPXDKRRIE-UHFFFAOYSA-NCetirizine hydrochloride is a potent second generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen induced asthma. Cetirizine hydrochloride is a carboxylated metabolite of hydroxyzine that acts as a selective Histamine H1 receptor inverse agonist. Compared to its parent compound, it shows similar antihistaminic activity, but with greater H1 selectivity and less sedative effects.

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